• Corpus ID: 249605325

Quantification of follow-up time in oncology clinical trials with a time-to-event endpoint: Asking the right questions

@inproceedings{Rufibach2022QuantificationOF,
  title={Quantification of follow-up time in oncology clinical trials with a time-to-event endpoint: Asking the right questions},
  author={Kaspar Rufibach and Lynda M Grinsted and Jiang Li and Hans-Jochen Weber and Cheng Zheng and Jiangxiu Zhou},
  year={2022}
}
For the analysis of a time-to-event endpoint in a single-arm or randomized clinical trial it is generally perceived that interpretation of a given estimate of the survival function, or the comparison between two groups, hinges on some quantification of the amount of follow-up. Typically, a median of some loosely defined quantity is reported. However, whatever median is reported, is typically not answering the question(s) trialists actually have in terms of follow-up quantification. In this…