Quantification of extrapulmonary translocation of intratracheal-instilled particles in vivo in rats: effect of lipopolysaccharide.

@article{Chen2006QuantificationOE,
  title={Quantification of extrapulmonary translocation of intratracheal-instilled particles in vivo in rats: effect of lipopolysaccharide.},
  author={Jianmin Chen and Mingguang Tan and Abderrahim Nemmar and Weiming Song and Mo Dong and Guilin Zhang and Yan Li},
  journal={Toxicology},
  year={2006},
  volume={222 3},
  pages={195-201}
}
Particulate air pollution is associated with respiratory and cardiovascular morbidity and mortality. However, important uncertainties remain in the quantification of extrapulmonary translocation of ultrafine particles into blood circulation. Therefore, the widely used radioiodinated technique was applied to radiolabel polystyrene particles with an average diameter of 56.4 and 202 nm, respectively. The extrapulmonary distribution of these particles (3.7 x 10(5) Bq/rat) was quantified at 0.5, 2… CONTINUE READING
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