Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm.

@article{Callender2007QuantificationOD,
  title={Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm.},
  author={Hannah L Callender and Jeffrey S Forrester and Pavlina T. Ivanova and Anita M Preininger and Stephen B. Milne and Haley A Brown},
  journal={Analytical chemistry},
  year={2007},
  volume={79 1},
  pages={263-72}
}
Diacylglycerols (DAGs) play significant roles in both intermediate metabolism and signal transduction. These lipid species are second messengers involved in modulating a plethora of cellular processes. Evaluation of DAG species concentrations has been hampered by the lack of a reliable method for molecular species analysis within a complex mixture of cellular lipids. We describe a new method for quantitative analysis of DAG species from complex biological extracts based on positive mode… CONTINUE READING

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