Quantification of collagen alteration in mid-dermis of skin lesion with mucinosis using second harmonic generation imaging

Cutaneous mucinoses are a heterogeneous group of diseases characterized by abnormal deposition of dermal mucin. Considering the collagen disorder due to the mucin deposition, collagen microstructure was visualized by second harmonic generation (SHG) microscopy to gain structural and diagnostic information. High resolution images of collagen in the dermis of… CONTINUE READING