Quantification of cells expressing the thyrotropin receptor in extraocular muscles in thyroid associated orbitopathy.

@article{Boschi2005QuantificationOC,
  title={Quantification of cells expressing the thyrotropin receptor in extraocular muscles in thyroid associated orbitopathy.},
  author={Artur Boschi and Chantal Daumerie and Micheline Spiritus and Cl Beguin and Maximin S{\`e}nou and Dilek Yuksel and M Duplicy and Sabine Costagliola and Marian Ludgate and Marie C. Many},
  journal={The British journal of ophthalmology},
  year={2005},
  volume={89 6},
  pages={724-9}
}
BACKGROUND/AIM Thyroid associated orbitopathy (TAO) and Graves' disease (GD) have an autoimmune pathogenesis, possibly related to the thyrotropin receptor (TSHR). The aim of this study was to determine whether TSHR immunoreactivity is correlated with disease severity or serum TSHR antibody (TRAB) levels. METHODS Orbital tissues from 30 patients with TAO were compared with those of 20 patients with strabismus and four with non-thyroid orbital inflammation. TSHR was detected by… CONTINUE READING

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The combination of absent thyroid peroxidase antibodies and high thyroid - stimulating immunoglobulin levels in Graves ’ disease identifies a group at markedly increased risk of ophthalmopathy

Khoo DHC, SC Ho, LL Seah
Thyroid • 1999

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