Quantification of calcium signal transmission from sarco-endoplasmic reticulum to the mitochondria.

@article{Pacher2000QuantificationOC,
  title={Quantification of calcium signal transmission from sarco-endoplasmic reticulum to the mitochondria.},
  author={P{\'a}l Pacher and Peter Csordas and Toni Schneider and Gy{\"o}rgy Hajn{\'o}czky},
  journal={The Journal of physiology},
  year={2000},
  volume={529 Pt 3},
  pages={
          553-64
        }
}
Recent studies have shown that ryanodine and IP3 receptor (RyR/IP3R)-mediated cytosolic Ca2+ signals propagate to the mitochondria, initiating chains of events vital in the regulation of different cellular functions. However, the fraction of released Ca2+ utilized by the mitochondria during these processes has not been quantified. To measure the amount of Ca2+ taken up by the mitochondria, we used a novel approach that involves simultaneous fluorescence imaging of mitochondrial and cytosolic… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 37 CITATIONS

Similar Papers

Loading similar papers…