Quantification of atorvastatin calcium in tablets by FT-Raman spectroscopy.

  title={Quantification of atorvastatin calcium in tablets by FT-Raman spectroscopy.},
  author={Sylwester Mazurek and Roman Szostak},
  journal={Journal of pharmaceutical and biomedical analysis},
  volume={49 1},
The FT-Raman quantification of atorvastatin calcium in tablets was performed using the partial least squares (PLS), principal component regression (PCR) and counter-propagation artificial neural networks (CP-ANN) methods. To compare the predictive abilities of the elaborated models, the relative standard errors of prediction (RSEP) were calculated. The application of PLS, PCR and 6x6 CP-ANN provided models of comparable quality. RSEP error values in the range of 1.9-2.8% for calibration and… CONTINUE READING


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