Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis

@article{Wang2020QuantificationOA,
  title={Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis},
  author={Zhiying Wang and Liangqiao Bian and C. Mo and H. Shen and L. J. Zhao and Kuan-Jui Su and Maciej Kukuła and Jauh Tzuoh Lee and D. Armstrong and R. Recker and J. Lappe and L. Bonewald and H. Deng and M. Brotto},
  journal={Communications Biology},
  year={2020},
  volume={3}
}
Osteoporosis is a highly prevalent chronic aging-related disease that frequently is only detected after fracture. We hypothesized that aminobutyric acids could serve as biomarkers for osteoporosis. We developed a quick, accurate, and sensitive screening method for aminobutyric acid isomers and enantiomers yielding correlations with bone mineral density (BMD) and osteoporotic fracture. In serum, γ-aminobutyric acid (GABA) and (R)-3-aminoisobutyric acid ( D -BAIBA) have positive associations with… Expand
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References

SHOWING 1-10 OF 76 REFERENCES
Tests of Linkage and/or Association of Genes for Vitamin D Receptor, Osteocalcin, and Parathyroid Hormone With Bone Mineral Density
  • H. Deng, H. Shen, +4 authors R. Recker
  • Biology, Medicine
  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2002
  • 119
Exercise interventions: defusing the world's osteoporosis time bomb.
  • 133
  • PDF
Relationship of sarcopenia and body composition with osteoporosis
  • 101
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease.
  • 48
...
1
2
3
4
5
...