Quantification of High-Resolution 1H-[13C] NMR Spectra from Rat Brain Extracts

Abstract

Extracting quantitative information about absolute concentrations from high-resolution (1)H NMR spectra of complex mixtures such as brain extracts remains challenging. Partial overlap of resonances complicates integration, whereas simple line fitting algorithms cannot accommodate the spectral complexity of coupled spin systems. Here, it is shown that high… (More)
DOI: 10.1021/ac102285c

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