Quantification of Heterogeneity as a Biomarker in Tumor Imaging: A Systematic Review

@inproceedings{Alic2014QuantificationOH,
  title={Quantification of Heterogeneity as a Biomarker in Tumor Imaging: A Systematic Review},
  author={Lejla Alic and Wiro J. Niessen and Jifke F. Veenland and Christos Hatzis},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Many techniques are proposed for the quantification of tumor heterogeneity as an imaging biomarker for differentiation between tumor types, tumor grading, response monitoring and outcome prediction. However, in clinical practice these methods are barely used. This study evaluates the reported performance of the described methods and identifies barriers to their implementation in clinical practice. METHODOLOGY The Ovid, Embase, and Cochrane Central databases were searched up to 20… CONTINUE READING