Quantification of Eosinophilic Granule Protein Deposition in Biopsies of Inflammatory Skin Diseases by Automated Image Analysis of Highly Sensitive Immunostaining

Abstract

Eosinophilic granulocytes are major effector cells in inflammation. Extracellular deposition of toxic eosinophilic granule proteins (EGPs), but not the presence of intact eosinophils, is crucial for their functional effect in situ. As even recent morphometric approaches to quantify the involvement of eosinophils in inflammation have been only based on cell… (More)

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Cite this paper

@inproceedings{Kiehl1999QuantificationOE, title={Quantification of Eosinophilic Granule Protein Deposition in Biopsies of Inflammatory Skin Diseases by Automated Image Analysis of Highly Sensitive Immunostaining}, author={Peter Kiehl and Katrin Falkenberg and Markus Vogelbruch and Alexander Kapp}, booktitle={Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology}, year={1999} }