Quantification of Ebola virus replication kinetics in vitro

  title={Quantification of Ebola virus replication kinetics in vitro},
  author={Laura E. Liao and Jonathan Carruthers and Sophie Smither and Simon A Weller and Diane Williamson and Thomas R. Laws and Isabel Garc{\'i}a-Dorival and Julian A. Hiscox and Benjamin P. Holder and Catherine A. A. Beauchemin and Alan S. Perelson and Mart{\'i}n L{\'o}pez-Garc{\'i}a and Grant D. Lythe and John N. Barr and Carmen Molina-Par{\'i}s},
  journal={PLoS Computational Biology},
Mathematical modelling has successfully been used to provide quantitative descriptions of many viral infections, but for the Ebola virus, which requires biosafety level 4 facilities for experimentation, modelling can play a crucial role. Ebola virus modelling efforts have primarily focused on in vivo virus kinetics, e.g., in animal models, to aid the development of antivirals and vaccines. But, thus far, these studies have not yielded a detailed specification of the infection cycle, which could… 

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