Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation

@article{Casas2012QuantificationOD,
  title={Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation},
  author={Christiane Casas and Carle Paul and M. Lahfa and Bulai Livideanu and Oph{\'e}lie Lejeune and Sandrine Alvarez-Georges and Christine Saint-Martory and Arnaud Degouy and Val{\'e}rie Mengeaud and Hervé Ginisty and E Durbise and Anne Marie Schmitt and Daniel Redoules},
  journal={Experimental Dermatology},
  year={2012},
  volume={21}
}
The aim of this study is to quantify D. folliculorum colonisation in rosacea subtypes and age‐matched controls and to determine the relationship between D. folliculorum load, rosacea subtype and skin innate immune system activation markers. We set up a multicentre, cross‐sectional, prospective study in which 98 adults were included: 50 with facial rosacea, including 18 with erythematotelangiectatic rosacea (ETR), and 32 with papulopustular rosacea (PPR) and 48 age‐ and sex‐matched healthy… Expand
Comparison of the Prevalences of Demodex folliculorum in Rosacea and Seborrhoeic Dermatitis with Standardized Skin Surface Biopsy
Objective: Rosacea (RSC) and seborrhoeic dermatitis (SD) are inflammatory dermatological conditions which are located in sebaceous gland-rich areas. Demodex folliculorum (D folliculorum) is the mostExpand
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A case-control study comparing cases with facial dermatoses with controls with healthy skin using denaturing gradient gel electrophoresis technique suggests that the bacteria in Demodex should come from the matched facial skin bacteria. Expand
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Preliminary results on the microbiota of Demodex mites based on a molecular approach showing an unexpected diversity are reported, which should open new perspectives for diagnostic of rosacea. Expand
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The quantification of D. folliculorum in human patients through molecular techniques such as polymerase chain reaction (PCR) has been described only in studies designed to address rosacea, and a higher prevalence of mites was detected in BCC of the inner canthus. Expand
Demodex folliculorum infestations in common facial dermatoses: acne vulgaris, rosacea, seborrheic dermatitis☆☆☆
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