Quantification from highly drifted and overlapped chromatographic peaks using second-order calibration methods.

@article{Comas2004QuantificationFH,
  title={Quantification from highly drifted and overlapped chromatographic peaks using second-order calibration methods.},
  author={Enric Comas and Roger Gimeno and Joan Ferr{\'e} and Rosa Maria Marc{\'e} and Francesc Borrull and F. Xavier Rius},
  journal={Journal of chromatography. A},
  year={2004},
  volume={1035 2},
  pages={195-202}
}
For determining low levels of pesticides and phenolic compounds in river and wastewater samples by high performance liquid chromatography (HPLC), solid phase extraction (SPE) is commonly used before the chromatographic separation. This preconcentration step is not necessarily selective for the analytes of interest and it may retain other compounds of similar characteristics as well. In this case, we present, humic and fulvic acids caused a large baseline drift and overlapped the analytes to be… CONTINUE READING