Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.

@article{Ward2007QuantificationAL,
  title={Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.},
  author={Scott Matthew Ward and Bridget C. Fox and Philip JB Brown and Joy Worthington and Stephen B. Fox and Roger William Chapman and K. A. Fleming and Alison H Banham and Paul Klenerman},
  journal={Journal of hepatology},
  year={2007},
  volume={47 3},
  pages={
          316-24
        }
}
BACKGROUND/AIMS T lymphocyte-mediated immune reactions are closely involved in the pathogenesis of HCV-induced chronic liver disease. Regulatory T cells are able to suppress HCV-specific T lymphocyte proliferation and cytokine secretion during chronic HCV infection. We wished to address to what extent regulatory T cells exist in the livers of HCV+ individuals, and what the role of such cells might be in disease progression. METHODS We analysed the frequency and distribution of FOXP3+ cells… CONTINUE READING
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Regulatory T cells in the control of host-microorganism interactions (*).

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