Quality-of-life results for accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation in early breast cancer after breast-conserving surgery (GEC-ESTRO): 5-year results of a randomised, phase 3 trial.

@article{Schfer2018QualityoflifeRF,
  title={Quality-of-life results for accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation in early breast cancer after breast-conserving surgery (GEC-ESTRO): 5-year results of a randomised, phase 3 trial.},
  author={Rebekka Sch{\"a}fer and Vratislav Strnad and Csaba Polg{\'a}r and Wolfgang Uter and Guido Hildebrandt and Oliver Ott and Daniela Kauer-Dorner and Hellen Knauerhase and Tibor Major and Jaroslaw Lyczek and Jose Luis Guinot and Juergen Dunst and Cristina Guti{\'e}rrez Migu{\'e}lez and Pavel {\vS}lampa and Michael Allgaeuer and Kristina Loessl and Gy{\"o}rgy J. Kov{\'a}cs and A. Fischedick and Rainer Fietkau and Alexandra Resch and Anna Kulik and L A Arribas and Peter Niehoff and Ferran Guedea and Annika Schlamann and Christine M Gall and Buelent Polat},
  journal={The Lancet. Oncology},
  year={2018},
  volume={19 6},
  pages={
          834-844
        }
}
BACKGROUND Previous results from the GEC-ESTRO trial showed that accelerated partial breast irradiation (APBI) using multicatheter brachytherapy in the treatment of early breast cancer after breast-conserving surgery was non-inferior to whole-breast irradiation in terms of local control and overall survival. Here, we present 5-year results of patient-reported quality of life. METHODS We did this randomised controlled phase 3 trial at 16 hospitals and medical centres in seven European… CONTINUE READING