Quality-of-life measurement in randomized clinical trials in breast cancer: an updated systematic review (2001-2009).

BACKGROUND Quality-of-life (QOL) measurement is often incorporated into randomized clinical trials in breast cancer. The objectives of this systematic review were to assess the incremental effect of QOL measurement in addition to traditional endpoints (such as disease-free survival or toxic effects) on clinical decision making and to describe the extent of… CONTINUE READING