Quality of life in pediatric asthma patients and their parents: a meta-analysis on 20 years of research

  title={Quality of life in pediatric asthma patients and their parents: a meta-analysis on 20 years of research},
  author={Neuza Silva and Carlos Carona and Carla Crespo and Maria Cristina Canavarro},
  journal={Expert Review of Pharmacoeconomics \& Outcomes Research},
  pages={499 - 519}
Introduction: This meta-analytic review was conducted to estimate the magnitude of quality of life (QoL) impairments in children/adolescents with asthma and their parents. Method: A systematic search in four electronic databases revealed 15 quantitative studies published between 1994–2013 that directly compared the QoL of 7- to 18-year-old asthma patients/parents to community/healthy controls. Pooled mean differences (MD) with 95% CI were estimated using the inverse-variance random-effects… 
Do 8- to 18-year-old children/adolescents with chronic physical health conditions have worse health-related quality of life than their healthy peers? a meta-analysis of studies using the KIDSCREEN questionnaires
The identification of significant HrQoL impairments among pediatric patients, specifically in the physical and social domains, highlights the importance of routine psychosocial assessment and intervention in primary pediatric healthcare services.
(Health-related) quality of life and psychosocial factors in adolescents with chronic disease: a systematic literature review
It is highly suggested to routinely assess HRQoL/psychosocial factors within an individualized framework, to considerer adolescents as a single/independent group, to emphasize potential protective factors, and, to increase youth’s participation in their own adaptation process and in health promotion in general.
Evaluation of quality of life according to asthma control and asthma severity in children and adolescents
Quality of life appears to be directly related to asthma control and asthma severity in children and adolescents, being better when asthma is well controlled and allergy severity is lower.
Quality of life among parents seeking treatment for their child’s functional abdominal pain
Physical HRQoL is not impaired in the majority of parents seeking treatment for their child's functional abdominal pain, however, the time demands and worries due to the child’s pain deserve specific attention.
Primary and Secondary Caregiver Reports of Quality of Life in Pediatric Asthma: Are they Comparable?
Differences in QOL scores between caregivers may be a reflection of primary caregivers’ greater investment in daily asthma management and in families reporting low burden and few psychological difficulties in the primary caregiver, QOL assessments from either caregiver may may be informative and representative of how parents are adapting to child asthma.
[Structural Equation Model of Health-Related Quality of Life in School Age Children with Asthma].
Strategies for promoting self-efficacy and enforcing asthma knowledge will be helpful for the improvement of health-related quality of life with school-aged asthmatic children.
Measuring health-related quality of life in young children with physical illness: psychometric properties of the parent-reported KIDSCREEN-27
Evidence of adequate psychometrics for the KIDSCREEN-27 in young children with chronic physical illness is provided, and measurement invariance testing and discriminant and convergent validity assessments are conducted.
The usefulness of a condition-specific measure (child-report) for the evaluation of the adaptation of children with asthma
The results showed that the asthma module assesses unique aspects of living with asthma and is more sensitive to asthma severity than the generic module, showing its usefulness in clinical practice.
Mapping the caregiving process in paediatric asthma: Parental burden, acceptance and denial coping strategies and quality of life
Broad-spectrum family-centred interventions in paediatric asthma settings can target the development of the parents’ coping tendencies characterised by greater acceptance and less denial as a way of reappraising caregiving demands as less burdensome and improving their QoL.


A comparison of quality of life in adolescents with epilepsy or asthma using the Short-Form Health Survey (SF-36)
Comparison of quality of life between asthmatic and healthy school children
A child's asthma impairs the quality of life (QoL) and especially the physical dimensions, and symptoms during longer periods were associated with an overall decreased QoL.
Psychological and quality of life outcomes in pediatric populations: a parent-child perspective.
Measuring quality of life in the parents of children with asthma
The Paediatric Asthma Caregiver's Quality of Life Questionnaire functions well as both an evaluative and a discriminative instrument and showed acceptable levels of longitudinal and cross-sectional correlations with the child's asthma status and health-related quality of life and with other measures of caregiver health- relatedquality of life.
Uncontrolled asthma: assessing quality of life and productivity of children and their caregivers using a cross-sectional Internet-based survey
Poorly controlled asthma symptoms impair HRQOL of children, QOL of their caregivers, and productivity of both, and proper treatment and management to improve symptom control may reduce humanistic and economic burdens on asthmatic children and their caregivers.
The impact of inadequately controlled asthma in urban children on quality of life and productivity.
Health-related quality of life problems of children aged 8–11 years with a chronic disease
It is concluded that using an indicator variable of the norm 25th percentile seems important in identifying at-risk children with chronic disease.
Health-related quality of life in Australian children with asthma: lessons for the cross-cultural use of quality of life instruments
Comparison with the UK data revealed that the non-asthmatic scores were higher for Australian than British children but that the scores for children with asthma did not differ between the two countries, and findings were interpreted in the context of cultural expectations of life quality.
Quality of Life in Young Urban Children: Does Asthma Make a Difference?
No differences were found in HRQL based on having current asthma or the severity of asthma as assessed by proxy measures of health care utilization and limited functioning, consistent with previous research indicating that HRQL is influenced by several factors other than asthma status and severity.
The reproducibility of the Childhood Asthma Questionnaires: measures of quality of life for children with asthma aged 4–16 years
Internal consistency varied widely but was higher for older children and longer subscales, and Implications of the findings for the use of the questionnaires in the evaluation of new asthma treatments are discussed.