Quality of epidural blockade. II. Influence of physico-chemical factors; hyaluronidase and potassium.

@article{Bromage1966QualityOE,
  title={Quality of epidural blockade. II. Influence of physico-chemical factors; hyaluronidase and potassium.},
  author={PhilipR. Bromage and Michael F. Burfoot},
  journal={British journal of anaesthesia},
  year={1966},
  volume={38 11},
  pages={
          857-65
        }
}
SUMMARY A trial was made of hyaluronidase and potassium chloride as adjuvants for epidural analgesia in 137 patients. Lignocaine hydrochloride in 2 per cent concentration with adrenaline 1/200,000 was used as the control solution in 61 cases; hyaluronidase, 5 USP units/ml, was added in 26 cases, and 1 per cent potassium chloride was added in 50 cases. Hyaluronidase tended to impair the quality of sensory blockade rather than to enhance it, whereas 1 per cent potassium chloride gave rise to a… CONTINUE READING

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