Quality of embryonic bodies and seeding density effects on neural differentiation of mouse embryonic stem cells.

@article{Zhou2008QualityOE,
  title={Quality of embryonic bodies and seeding density effects on neural differentiation of mouse embryonic stem cells.},
  author={Jun-mei Zhou and Feng-Ying Xing and Jian-Jun Shi and Zhen-Fu Fang and Xue-jin Chen and Fang Chen},
  journal={Cell biology international},
  year={2008},
  volume={32 9},
  pages={
          1169-75
        }
}
Mouse embryonic stem (ES) cells can be differentiated into neural lineage cells, but the differentiation efficiency remains low. This study revealed two important factors that influence the neural differentiation efficiency of mouse ES cells: the first is the quality of embryonic bodies (EBs); good quality of EBs consistently originated from a suspension culture of 1x10(5) ES cells/ml serum-free chemically defined neural inducing medium and they exhibited a smooth round shape, with a dark… CONTINUE READING
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