Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy.

@article{Fan2012QualityEA,
  title={Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy.},
  author={Gang Fan and Meng Zhang and Xiang-dong Zhou and Xianrong Lai and Qing-hong Yue and Ce Mun Tang and Wei-zao Luo and Yong-fang Zhang},
  journal={Analytica chimica acta},
  year={2012},
  volume={747},
  pages={
          76-83
        }
}
Rhizoma coptidis, a broadly used traditional Chinese medicine, derives from the dried rhizomes of Coptis chinensis Franch, Coptis deltoidea C.Y. Cheng et Hsiao and Coptis teeta Wall. Quantitative determination of protoberberine alkaloids in R. coptidis is critical for controlling its quality. In this study, a rapid, simple and accurate quantitative (1)H NMR (qNMR) method was developed for simultaneous determination of berberine, jatrorrhizine, epiberberine, coptisine, palmatine and columbamine… Expand
Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity
TLDR
Various investigations have shown that CR and its main alkaloids exhibited many powerful pharmacological effects including anti-inflammatory, anti-cancer, anti -diabetic, neuroprotective, cardioprotective, hypoglycemic,Anti-Alzheimer and hepatoprotective activities. Expand
Histochemical evaluation of alkaloids in rhizome of Coptis chinensis using laser microdissection and liquid chromatography/mass spectrometry.
TLDR
Histochemical evaluation on bioactive components of Coptidis Rhizoma in anatomic sections using laser microdissection and liquid chromatography-mass spectrometry (LMD-LC-MS) was developed to correlate the inner quality and outer features of materials from different growing areas. Expand
Comprehensive analyses of molecular phylogeny and main alkaloids for Coptis (Ranunculaceae) species identification
TLDR
In this study, the phylogenetic relationships within the genus Coptis from China are resolved with high support and evidence is provided that the relationships inferred by chemical taxonomy are different to those of the present molecular phylogeny. Expand
Metabolic discrimination of sea buckthorn from different Hippophaë species by 1H NMR based metabolomics
TLDR
1H NMR-based metabolomics is an applicable and effective approach for simultaneous metabolic profiling, species differentiation and quality assessment and showed that different Hippophaë species can be clearly discriminated. Expand
Construction of an optimized method for quality evaluation and species discrimination of Coptidis Rhizoma by ion‐pair high performance liquid chromatography combined with response surface methodology
TLDR
An optimized method for quality evaluation and species discrimination of CR is constructed by ion‐pairing high performance liquid chromatography (IP‐HPLC) combined with response surface methodology (RSM) and a single standard to determine multi‐components method is developed. Expand
Identification and Characterization of Genes Involved in Benzylisoquinoline Alkaloid Biosynthesis in Coptis Species
TLDR
The integration of the transcriptome and enzyme activity assays further provides new insight into molecular mechanisms underlying BIA biosynthesis in plants and identifies candidate genes for the study of synthetic biology in microorganisms. Expand
Metabolic discrimination of Swertia mussotii and Swertia chirayita known as "Zangyinchen" in traditional Tibetan medicine by (1)H NMR-based metabolomics.
TLDR
Findings indicate that (1)H NMR-based metabolomics is a reliable and effective method for the metabolic profiling and discrimination of the two Swertia species, and can be used to verify the genuine origin of Zangyinchen. Expand
The similarity and variability of the iridoid glycoside profile and antioxidant capacity of aerial and underground parts of Lamiophlomis rotata according to UPLC-TOF-MS and multivariate analyses
TLDR
The results suggest the dosage should be increased when the aerial parts of the plant are used as crude medicinal materials instead of the underground parts, and the content of total IGs and the antioxidant capacity were investigated in samples from different locations. Expand
Discriminating Lamiophlomis rotata According to Geographical Origin by (1)H-NMR Spectroscopy and Multivariate Analysis.
TLDR
The NMR-based analysis of L. rotata is a more comprehensive approach than traditional chromatographic methods, and simple sample preparation, rapidity and reproducibility of are additional advantages of NMR analysis. Expand
Process characterization for ethanol precipitation of Salviae miltiorrhizae Radix et Rhizoma (Danshen) using 1H NMR spectroscopy and chemometrics
Abstract Process quality control of the herbal medicines (HMs) still hits technical bottlenecks due to their complicated multi-step pretreating. Nuclear magnetic resonance (NMR) spectroscopy couldExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 36 REFERENCES
Metabolic discrimination of rhizoma coptidis from different species using 1H NMR spectroscopy and principal component analysis.
TLDR
It is indicated that metabolites of rhizoma coptidis vary with the species and the proposed method is suitable for metabolic fingerprinting analysis to check the genuine origin of rhzomaCoptidis. Expand
Determination of protoberberine alkaloids in Rhizoma Coptidis by ERETIC ¹H NMR method.
TLDR
The high universality, accuracy, reproducibility, and efficiency of the ERETIC method demonstrated in this work suggest that this method could serve as a highly potential quantification alternative for quality assessment of TCM. Expand
A rapid and simple determination of protoberberine alkaloids in Rhizoma Coptidis by 1H NMR and its application for quality control of commercial prescriptions.
TLDR
A highly specific and sensitive method using (1)H NMR has been developed for the quantitative determination of protoberberine alkaloids berberine, palmatine, coptisine and jatrorrhizine in Coptis species and their commercial traditional Chinese medicine prescriptions. Expand
Application of 1H-NMR spectroscopy to validation of berberine alkaloid reagents and to chemical evaluation of Coptidis Rhizoma
TLDR
The purity of the reagent estimated by the 1H-NMR was, in general, lower than that claimed by the manufacturer, leading to over-estimation of the alkaloid contents of Coptidis Rhizoma when determined by HPLC. Expand
Comparative quantitative analysis of artemisinin by chromatography and qNMR.
TLDR
These results imply that qNMR, with the addition of an internal standard, can be used to quantify artemisinin in A. annua samples in a rapid and reproducible manner. Expand
Applications of microcalorimetry in the antibacterial activity evaluation of various Rhizoma coptidis
TLDR
This work provided a useful method for the evaluation of antibacterial activity of various R. coptidis in dried roots of Coptis chinensis Franch, Coptis deltoidea, and Coptis teeta Wall together with statistical analysis. Expand
Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase
TLDR
The results clearly indicated that Coptidis Rhizoma, and the alkaloids contained therein, would clearly have beneficial uses in the development of therapeutic and preventive agents for diabetic complications and diabetes mellitus. Expand
Identification and quantification of the main organic components of vinegars by high resolution 1H NMR spectroscopy.
TLDR
The (1)H NMR method proposed was applied to different samples of Vinegars, allowing, in particular, the discrimination of vinegars and balsamic vinegars, and good correlations were obtained. Expand
Micellar electrokinetic chromatography for separation of a mixture of coptis alkaloids, scute flavonoids, and rhubarb anthraquinones and bianthrones.
TLDR
A method to assess San-huang-xie-xin-tang within short analysis time and also provided a possible starting point to evaluate related herbal preparations containing Coptidis Rhizoma, Scutellariae Radix, and RheiRhizoma is proposed. Expand
Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry.
TLDR
The inhibitory effects of BA on E. coli revealed that the sequence of their antimicrobial activity was berberine > coptisine > palmatine, and the functional groups methylenedioxy at C2 and C3 on phenyl ring improve antimacterial activity more remarkably than methoxyl at C1 and C2 on Phenyl ring. Expand
...
1
2
3
4
...