Quality control of CGH: impact of metaphase chromosomes and the dynamic range of hybridization.

Abstract

With the recent rapid expansion in the use of the comparative genomic hybridization (CGH) technique, increased attention to quality control is essential. In the present study, we show that despite optimization and standardization of metaphase preparation techniques and the commercial availability of metaphase spreads, batch-to-batch variability of the… (More)

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Cite this paper

@article{Karhu1997QualityCO, title={Quality control of CGH: impact of metaphase chromosomes and the dynamic range of hybridization.}, author={Ritva Karhu and Marketta K{\"a}hk{\"o}nen and Tuula Kuukasj{\"a}rvi and Sirpa M A Pennanen and Mika Tirkkonen and Olli Kallioniemi}, journal={Cytometry}, year={1997}, volume={28 3}, pages={198-205} }