Quality assurance of dosimetry and the impact on sample size in randomized clinical trials.

Abstract

BACKGROUND AND PURPOSE The aim of this study was to investigate the impact of appropriate dosimetry quality assurance (QA) on patient number required in radiotherapy randomized control trials (RCT). MATERIALS AND METHODS The steepness of clinical dose-response curves, gamma(clin.), was calculated by a convoluting a biological dose-response distribution… (More)

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