Quality and Safety Requirements for Sustainable Phage Therapy Products

  title={Quality and Safety Requirements for Sustainable Phage Therapy Products},
  author={Jean-Paul Pirnay and Bob G. Blasdel and Laurent Bretaudeau and Angus Buckling and Nina Chanishvili and Jason R. Clark and Sofia Corte-Real and Laurent Debarbieux and Alain Dublanchet and Daniel De Vos and J{\'e}r{\^o}me Gabard and Miguel Latorre Garc{\'i}a and Marina Goderdzishvili and Andrzej G{\'o}rski and John Hardcastle and Isabelle Huys and Elizabeth Kutter and Rob Lavigne and Maia Merabishvili and Ewa Olchawa and Kaarle J. Parikka and Olivier Patey and Flavie Pouilot and Gr{\'e}gory Resch and Christine Rohde and Jacques Scheres and Mikael Skurnik and Mario Vaneechoutte and Luc Van Parys and Gilbert Verbeken and Martin Zizi and Guy L M Van Den Eede},
  booktitle={Pharmaceutical Research},
The worldwide antibiotic crisis has led to a renewed interest in phage therapy. Since time immemorial phages control bacterial populations on Earth. Potent lytic phages against bacterial pathogens can be isolated from the environment or selected from a collection in a matter of days. In addition, phages have the capacity to rapidly overcome bacterial resistances, which will inevitably emerge. To maximally exploit these advantage phages have over conventional drugs such as antibiotics, it is… CONTINUE READING
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