Qualitative and quantitative ultrastructural observations on retinal ganglion cell layer of rat after intraorbital optic nerve crush.

@article{Barron1986QualitativeAQ,
  title={Qualitative and quantitative ultrastructural observations on retinal ganglion cell layer of rat after intraorbital optic nerve crush.},
  author={Kevin D. Barron and M. P. Dentinger and Gregory B Krohel and S K Easton and R F Mankes},
  journal={Journal of neurocytology},
  year={1986},
  volume={15 3},
  pages={345-62}
}
Rat retinal ganglion cell layer (GCL) was examined ultrastructurally 1-180 days after intraorbital crushing of one optic nerve. It was confirmed quantitatively that axotomized ganglion cells lost cisternal membranes of the rough endoplasmic reticulum (RER) and showed disintegration of Nissl bodies and ribosomal rosettes 3 days postoperatively. Between 60 and 180 days after neurotomy there was partial reversion of the RER towards normal. At postoperative intervals of 14-60 days, chromatin… CONTINUE READING