Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes

@inproceedings{Baca2017QualifiersOA,
  title={Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes},
  author={Sylvan Charles Baca and Kristine S Wong and Kyle C. Strickland and Howard T Heller and Matthew I. Kim and Justine A Barletta and Edmund S Cibas and Jeffrey F Krane and Ellen Marqusee and Trevor E Angell},
  booktitle={Cancer cytopathology},
  year={2017}
}
BACKGROUND Thyroid nodules with atypia of undetermined significance (AUS) on fine-needle aspiration (FNA) have a low risk of malignancy that appears to vary based on specific features described in the AUS diagnosis. The Afirma gene expression classifier (GEC) is a molecular test designed to improve preoperative risk stratification of thyroid nodules, but its performance for different patterns of AUS has not been defined. The objective of this study was to assess GEC results and clinical… CONTINUE READING
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