QUIT: QUantitative Imaging Tools

  title={QUIT: QUantitative Imaging Tools},
  author={Tobias C Wood},
  journal={Journal of Open Source Software},
  • Tobias C Wood
  • Published 21 June 2018
  • Journal of Open Source Software
MICRA: Microstructural image compilation with repeated acquisitions
Fast calculation software for modified Look-Locker inversion recovery (MOLLI) T1 mapping
The presented software tool (fT1fit) facilitated rapid T1 map and extracellular volume fraction map calculations and the C++ multi-core RD was the fastest method on a regular eight-core personal computer for pre- or post-contrast T1map calculation.
The innate immune toll-like-receptor-2 modulates the depressogenic and anorexiolytic neuroinflammatory response in obstructive sleep apnoea
By utilising multimodal imaging in this established model of OSA, a discernible neuroinflammatory response was demonstrated for the first time and the modulatory role for the functional TLR2-system was suggested in aetiology of depressive, anxious and anorexiolytic symptoms in OSA.
Silent T1 mapping using the variable flip angle method with B1 correction
To compare the silent rotating ultrafast imaging sequence (RUFIS) to a traditional Cartesian spoiled gradient‐echo (SPGR) acquisition scheme for variable flip angle (VFA) T1 mapping.
Magnetization transfer and frequency distribution effects in the SSFP ellipse
To demonstrate that quantitative magnetization transfer parameters can be extracted from steady‐state free‐precession (SSFP) data with no external T1 map or banding artifacts, data from three consecutive SSFP studies are analyzed.
QUIT: QUantitative Imaging Tools
This paper focuses on implementations of multiple quantitative MRI algorithms as command-line tools written in C++ and using the high-quality Insight Toolkit, and the recent qMRLab project, which provides a large variety of techniques written in Matlab.


An investigation of regional cerebral blood flow and tissue structure changes after acute administration of antipsychotics in healthy male volunteers
It is illustrated that a single clinically relevant oral dose of an antipsychotic has no detectable acute effect on T1 in healthy volunteers, and a methodology for applying quantitative imaging methods to assess the acute effects of other compounds on structural MRI metrics is provided.
Genome-Wide Transcriptional Profiling and Structural Magnetic Resonance Imaging in the Maternal Immune Activation Model of Neurodevelopmental Disorders
It is demonstrated that prenatal viral-like immune activation causes myelin-related transcriptional and epigenetic changes in corticostriatal areas of adult offspring exposed to prenatal immune activation.
Whole-brain ex-vivo quantitative MRI of the cuprizone mouse model
The whole brain of the cuprizone mouse ex-vivo is imaged and analyzed using high-resolution quantitative MR methods and changes in multiple regions are found, including the corpus callosum, cerebellum, thalamus and hippocampus.