QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients.

@article{Reilly2000QTcintervalAA,
  title={QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients.},
  author={Joseph Reilly and Salma Ayis and I. Nicol Ferrier and Steven J Jones and Simon H L Thomas},
  journal={Lancet},
  year={2000},
  volume={355 9209},
  pages={1048-52}
}
BACKGROUND Sudden unexplained death in psychiatric patients may be due to drug-induced arrhythmia, of which lengthening of the rate-corrected QT interval (QTc) on the electrocardiogram is a predictive marker. We estimated the point prevalence of QTc lengthening in psychiatric patients and the effects of various psychotropic drugs. METHODS Electrocardiograms were obtained from 101 healthy reference individuals and 495 psychiatric patients in various inpatient and community settings and were… CONTINUE READING

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