QTL analysis: a simple ‘marker-regression’ approach

@article{Kearsey1994QTLAA,
  title={QTL analysis: a simple ‘marker-regression’ approach},
  author={Michael J. Kearsey and V. Hyne},
  journal={Theoretical and Applied Genetics},
  year={1994},
  volume={89},
  pages={698-702}
}
A method to locate quantitative trait loci (QTL) on a chromosome and to estimate their additive and dominance effects is described. It applies to generations derived from an F1 by selfing or backcrossing and to doubled haploid lines, given that marker genotype information (RFLP, RAPD, etc.) and quantitative trait data are available. The method involves regressing the additive difference between marker genotype means at a locus against a function of the recombination frequency between that locus… CONTINUE READING
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