QT interval prolongation and the risk of torsades de pointes: essentials for clinicians.

  title={QT interval prolongation and the risk of torsades de pointes: essentials for clinicians.},
  author={Katy E Trinkley and Robert L. Page and Hoang Lien and Kevin Yamanouye and James E Tisdale},
  journal={Current medical research and opinion},
  volume={29 12},
OBJECTIVE QT interval prolongation signifies an increased risk of the life-threatening arrhythmia torsades de pointes (TdP). The purpose of this paper is to review the diverse methods for assessing and monitoring the risk of TdP, discuss risk factors for TdP, and recommend interventions that may mitigate the risk of TdP. METHODS A non-systematic search of PubMed (through March 2013) was conducted to determine the optimal approach to assessing and monitoring QT interval, prevention of TdP, and… CONTINUE READING


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