QSAR prediction of estrogen activity for a large set of diverse chemicals under the guidance of OECD principles.

@article{Liu2006QSARPO,
  title={QSAR prediction of estrogen activity for a large set of diverse chemicals under the guidance of OECD principles.},
  author={Huanxiang Liu and Ester Papa and Paola Gramatica},
  journal={Chemical research in toxicology},
  year={2006},
  volume={19 11},
  pages={1540-8}
}
A large number of environmental chemicals, known as endocrine-disrupting chemicals, are suspected of disrupting endocrine functions by mimicking or antagonizing natural hormones, and such chemicals may pose a serious threat to the health of humans and wildlife. They are thought to act through a variety of mechanisms, mainly estrogen-receptor-mediated mechanisms of toxicity. However, it is practically impossible to perform thorough toxicological tests on all potential xenoestrogens, and thus… CONTINUE READING

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