QSAR Study on Arylthioquinoline Derivatives as Anti-tubercular Agents

  title={QSAR Study on Arylthioquinoline Derivatives as Anti-tubercular Agents},
  author={Veerasamy Ravichandran and Sivadasan Shalini and Krishnamoorthi Venaktes Kumar and Rajak Harish and Krishnan Suresh Kumar},
Aim: The major issue for many anti-tubercular agents is the resistance of Mycobacterium tuberculosis strains. Quinoline compounds serve as anti-mycobacterial agents with encouraging anti-tubercular activity. The main aim of this study is to develop 2D QSAR models for a series of arylthioquinoline to predict their ideal characteristics as potential anti-tubercular agents. Materials and Methods: Used CS Chem Office 2004 and Molecular Modeling Pro 6.1.0 software for modeling and models development… 

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