QColors: An algorithm for conservative viral quasispecies reconstruction from short and non-contiguous next generation sequencing reads

@article{Huang2011QColorsAA,
  title={QColors: An algorithm for conservative viral quasispecies reconstruction from short and non-contiguous next generation sequencing reads},
  author={Austin Huang and Rami Kantor and Allison DeLong and Leeann Schreier and Sorin Istrail},
  journal={2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)},
  year={2011},
  pages={130-136}
}
Next generation sequencing technologies have been successfully applied to HIV-infected patients in order to obtain the mutational spectrum of heterogeneous viral populations within individuals, known as quasispecies. However, the metage-nomics problem of quasispecies sequence reconstruction from next generation sequencing reads is not-yet widely applied in current practice and remains an emerging area of research. Furthermore, the majority of research methodology in HIV has focused on 454… CONTINUE READING
Highly Cited
This paper has 32 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Quasispecies reconstruction based on vertex coloring algorithms

2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) • 2014
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID.

Proceedings of the National Academy of Sciences of the United States of America • 2011
View 2 Excerpts

First-line antiretroviral treatment effects on resistance mutation prevalence in HIV-1 subtypes

A. Huang, J. W. Hogan, +3 authors R. Kantor
6th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 2011. • 2011
View 1 Excerpt

A multicentre collaborative study on HIV drug resistance testing using 454 massively parallel pyrosequencing

B. B. Simen, M. Braverman, +13 authors M. Daumer
Antiviral Therapy, vol. 15 Supp, no. 2, p. A37, 2010. 135 • 2010

Similar Papers

Loading similar papers…