QCScreen: a software tool for data quality control in LC-HRMS based metabolomics

@article{Simader2015QCScreenAS,
  title={QCScreen: a software tool for data quality control in LC-HRMS based metabolomics},
  author={Alexandra Simader and Bernhard Kluger and Nora Katharina Nicole Neumann and Christoph Bueschl and Marc Lemmens and Gerald Lirk and Rudolf Krska and Rainer Schuhmacher},
  journal={BMC Bioinformatics},
  year={2015},
  volume={16},
  pages={1-9}
}
Metabolomics experiments often comprise large numbers of biological samples resulting in huge amounts of data. This data needs to be inspected for plausibility before data evaluation to detect putative sources of error e.g. retention time or mass accuracy shifts. Especially in liquid chromatography-high resolution mass spectrometry (LC-HRMS) based metabolomics research, proper quality control checks (e.g. for precision, signal drifts or offsets) are crucial prerequisites to achieve reliable and… CONTINUE READING
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