QA interval as an indirect measure of cardiac contractility in the conscious telemeterised rat: model optimisation and evaluation.

Abstract

INTRODUCTION Conscious telemeterised rats are used for early assessment of cardiovascular drug safety. This paper details the surgery required to allow key cardiovascular parameters to be determined and describes how QA interval (QAI), a surrogate measure of cardiac contractility, is related to a more direct measure of cardiac contractility, dP/dt(max… (More)
DOI: 10.1016/j.vascn.2009.03.006

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Cite this paper

@article{Adeyemi2009QAIA, title={QA interval as an indirect measure of cardiac contractility in the conscious telemeterised rat: model optimisation and evaluation.}, author={Oluwatoyin Falusi Adeyemi and S. Roberts and Joel M Harris and Hannah West and S. N. Shome and Matthew Richard Dewhurst}, journal={Journal of pharmacological and toxicological methods}, year={2009}, volume={60 2}, pages={159-66} }