Q Fever in Pregnant Goats: Pathogenesis and Excretion of Coxiella burnetii

@inproceedings{Roest2012QFI,
  title={Q Fever in Pregnant Goats: Pathogenesis and Excretion of Coxiella burnetii},
  author={H I J Roest and Betty van Gelderen and Annemieke Dinkla and Dimitrios Frangoulidis and Fred G. van Zijderveld and J. M. J. Rebel and Lucien J M van Keulen},
  booktitle={PloS one},
  year={2012}
}
Coxiella burnetii is an intracellular bacterial pathogen that causes Q fever. Infected pregnant goats are a major source of human infection. However, the tissue dissemination and excretion pathway of the pathogen in goats are still poorly understood. To better understand Q fever pathogenesis, we inoculated groups of pregnant goats via the intranasal route with a recent Dutch outbreak C. burnetii isolate. Tissue dissemination and excretion of the pathogen were followed for up to 95 days after… CONTINUE READING