Q&A: Systems biology

@article{Ferrell2009QASB,
  title={Q&A: Systems biology},
  author={James E Ferrell},
  journal={Journal of Biology},
  year={2009},
  volume={8},
  pages={2 - 2}
}
How complex are the systems that systems biologists study? That depends. Some people focus on networks at the ‘omics’-scale: whole genomes, proteomes, or metabolomes. These systems can be represented by graphs with thousands of nodes and edges (see Figure 1). Others focus on small subcircuits of the network; say a circuit composed of a few proteins that functions as an amplifier, a switch or a logic gate. Typically, the graphs of these systems possess fewer than a dozen (or so) nodes. Both the… CONTINUE READING
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