Pyruvate stabilizes electrocardiographic and hemodynamic function in pigs recovering from cardiac arrest

@article{Cherry2015PyruvateSE,
  title={Pyruvate stabilizes electrocardiographic and hemodynamic function in pigs recovering from cardiac arrest},
  author={Brandon H. Cherry and A. Nguyen and Roger A Hollrah and A. Williams and Besim Hoxha and A. Olivencia-Yurvati and R. Mallet},
  journal={Experimental Biology and Medicine},
  year={2015},
  volume={240},
  pages={1774 - 1784}
}
  • Brandon H. Cherry, A. Nguyen, +4 authors R. Mallet
  • Published 2015
  • Medicine
  • Experimental Biology and Medicine
  • Cardiac electromechanical dysfunction may compromise recovery of patients who are initially resuscitated from cardiac arrest, and effective treatments remain elusive. Pyruvate, a natural intermediary metabolite, energy substrate, and antioxidant, has been found to protect the heart from ischemia-reperfusion injury. This study tested the hypothesis that pyruvate-enriched resuscitation restores hemodynamic, metabolic, and electrolyte homeostasis following cardiac arrest. Forty-two Yorkshire swine… CONTINUE READING
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