Pyrrolizidine alkaloids from Cryptantha species

  title={Pyrrolizidine alkaloids from Cryptantha species},
  author={Frank R. Stermitz and M. A. Pass and Ronald B. Kelley and James R. Liddell},

Dehydropyrrolizidine alkaloids in two Cryptantha species: including two new open chain diesters one of which is amphoteric.

The retronecine-based alkaloids detected in both Cryptantha species herein investigated aligns them within the Krynitzkia subgenus, and the low levels in the plants potentially mitigate the risk.

Acquired and Partially De Novo Synthesized Pyrrolizidine Alkaloids in Two Polyphagous Arctiids and the Alkaloid Profiles of Their Larval Food-Plants

The profiles of pyrrolizidine alkaloids in the two highly polyphagous arctiids Estigmene acrea and Grammia geneura and their potential PA sources in southeastern Arizona were compiled and a number of novel insect PAs were identified.

Diversity of Pyrrolizidine Alkaloids in the Boraginaceae Structures, Distribution, and Biological Properties

This review reports the available information on the present status (literature up to early 2014) of the pyrrolizidine alkaloids in the Boraginaceae and summarizes the topics structure, distribution, chemistry, chemotaxonomic significance, and biological properties.

Detection of high levels of pyrrolizidine-N-oxides in the endangered plant Cryptantha crassipes (Terlingua Creek cat's-eye) using HPLC-ESI-MS.

The high levels of the N-oxides of lycopsamine and intermedine establish the genus chemotype of the endangered Cryptantha crassipes and support earlier data linking high levels in pyrrolizidine alkaloids to dry, harsh growing conditions.

Analysis of Pyrrolizidine Alkaloids in Queensland Honey: Using Low Temperature Chromatography to Resolve Stereoisomers and Identify Botanical Sources by UHPLC-MS/MS

Overall plant pyrrolizidine alkaloid profiles were compared to those found in honey samples to help identify the most important plants responsible for honey contamination, and the native Australian vines of Parsonsia spp.

Occurrence of halogenated alkaloids.

  • G. Gribble
  • Chemistry
    The Alkaloids. Chemistry and biology
  • 2012

Stereochemical Assignment of 2,3‐Epoxy‐2‐methylbutanoate Esters in Natural Products

Inspection of the 182 known natural products containing 2,3-epoxy-2-methylbutanoate ester residues revealed a very high tendency in nature for the preferential epoxidation of (Z)-2-methyl-2-butenoate



The alkaloids of Amsinckia species: A. intermedia Fisch. & Mey., A. hispida (Ruiz. & Pav.) Johnst. and A. lycopsoides Lehm

Hepatotoxic pyrrolizidine alkaloids have been isolated from Amsinckia species occurring in Victoria and in California. A. intermedia Fisch. & Mey. contains echumine and four new alkaloids,

The pyrrolizidine alkaloids of Amsinckia menziesii

Methanolic extracts of fresh Arnsinckia menziesii (Lehm.) Nels, and Macbr. (Boraginaceae) yielded three known pyrrolizidine alkaloids, intermedinet (I), lycopsaminet (2) and 7-acetyllycopsaminet (3).

The alkaloids of Echium plantagineum L

Two new alkaloids, echiumine, C20H31O6N, and echimidine, C20H31O7N, have been isolated from Echium plantagineum L. Both have a retronecine nucleus esterified on the 7-hydroxyl group with angelic