Corpus ID: 20892541

Pyrrolizidine alkaloid plants, metabolism and toxicity.

  title={Pyrrolizidine alkaloid plants, metabolism and toxicity.},
  author={B. Stegelmeier and J. Edgar and S. Colegate and D. Gardner and T. K. Schoch and R. Coulombe and R. Molyneux},
  journal={Journal of natural toxins},
  volume={8 1},
More than 350 PAs have been identified in over 6,000 plants in the Boraginaceae, Compositae, and Leguminosae families (Table 1). About half of the identified PAs are toxic and several have been shown to be carcinogenic in rodents. PA-containing plants have worldwide distribution, and they probably are the most common poisonous plants affecting livestock, wildlife, and humans. In many locations, PA-containing plants are introduced species that are considered invasive, noxious weeds. Both native… Expand
253 Citations
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