Pyrosequencing-based molecular monitoring of the intestinal bacterial colonization in preterm infants.

  title={Pyrosequencing-based molecular monitoring of the intestinal bacterial colonization in preterm infants.},
  author={Ju Yuong Chang and Son Moon Shin and Jongsik Chun and Jae-Hak Lee and Jeong-Kee Seo},
  journal={Journal of pediatric gastroenterology and nutrition},
  volume={53 5},
OBJECTIVES The aim of the study was to investigate the previously unexplored diversity of neonatal intestinal microbiota and monitor early intestinal colonization patterns in Korean preterm infants using high-throughput pyrosequencing technology combined with 16S rDNA-based molecular methods. SUBJECTS AND METHODS A total of 46,369 partial 16S rDNA sequences obtained from 30 fecal samples serially taken from 10 very-low-birth weight preterm infants were analyzed. RESULTS A significant… CONTINUE READING
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