Pyrimidine as Constituent of Natural Biologically Active Compounds

@article{Lagoja2005PyrimidineAC,
  title={Pyrimidine as Constituent of Natural Biologically Active Compounds},
  author={Irene M. Lagoja},
  journal={Chemistry \& Biodiversity},
  year={2005},
  volume={2}
}
  • I. Lagoja
  • Published 2005
  • Chemistry, Medicine
  • Chemistry & Biodiversity
This review describes the various manifestations of the pyrimidine system (alkylated, glycosylated, benzo‐annelated.). These comprise pyrimidine nucleosides as well as alkaloids and antibiotics – some of them have been discovered and isolated from natural sources already long time ago, others have been reported very recently. A short overview on pyrimidine syntheses (prebiotic synthesis, biosynthesis, and metabolism) is given. The biological activities of most of the pyrimidine analogs are… Expand
Pyrimidine as Constituent of Natural Biologically Active Compounds
This review describes the various manifestations of the pyrimidine system (alkylated, glycosylated, benzo-annelated.). These comprise pyrimidine nucleosides as well as alkaloids and antibiotics –Expand
Synthesis of Some Novel Chromenopyrimidine Derivatives and Evaluation of Their Biological Activities
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A series of chromenopyrimidine derivatives were synthesized by reaction of an intermediate imine and ammonia derivatives in good to high yields and the antibacterial activity of these compounds was investigated against Staphylococcus aureus and Escherichia Coli. Expand
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The pyrimidine moiety is one of the most widespread heterocycles in biologically occurring compounds, such as nucleic acids components (uracil, thymine and cytosine) and vitamin B1. Due to itsExpand
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These recently developed methodologies offer a valuable addendum to azaheterocycle synthesis, including N-C fragment condensation strategies, that provide reactive intermediates capable of intramolecular cyclization and formation of pyrimidine derivatives. Expand
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