Pyridoxine-dependent seizures: magnetic resonance spectroscopy findings.

  title={Pyridoxine-dependent seizures: magnetic resonance spectroscopy findings.},
  author={Alpay Alkan and Ramazan Kutlu and Mehmet G{\"o}khan Aslan and Ahmet Siğirci and Ismet Orkan and Cengiz Yakinci},
  journal={Journal of child neurology},
  volume={19 1},
Pyridoxine-dependent seizures are an extremely rare genetic disorder. Early diagnosis and treatment are important for the prevention of permanent brain damage. Elevated levels of glutamate and decreased levels of gamma-aminobutyric acid (GABA) in the frontal and parietal cortices are among the characteristic features of this disorder. These metabolic abnormalities eventually lead to seizures and neuronal loss. In this case report, we present magnetic resonance spectroscopy findings of a 9-year… CONTINUE READING