Pyridone and tetramic acid alkaloids from the spider pathogenic fungus Torrubiella sp. BCC 2165.

Abstract

Torrubiellones A-D (1-4), new pyridone and tetramic acid alkaloids, were isolated from the spider pathogenic fungus Torrubiella sp. BCC 2165. Torrubiellone A (1) exhibited antimalarial activity with an IC(50) value of 8.1 μM, while it showed very weak cytotoxic activity.

DOI: 10.1021/np100492j

Cite this paper

@article{Isaka2010PyridoneAT, title={Pyridone and tetramic acid alkaloids from the spider pathogenic fungus Torrubiella sp. BCC 2165.}, author={Masahiko Isaka and Panida Chinthanom and Sumalee Supothina and Punsa Tobwor and Nigel L. Hywel-Jones}, journal={Journal of natural products}, year={2010}, volume={73 12}, pages={2057-60} }