Pyrethroid-induced paresthesia--a central or local toxic effect?

  title={Pyrethroid-induced paresthesia--a central or local toxic effect?},
  author={Martin F. Wilks},
  journal={Journal of toxicology. Clinical toxicology},
  volume={38 2},
  • Martin F. Wilks
  • Published 2000 in Journal of toxicology. Clinical toxicology
BACKGROUND Pyrethroid-induced paresthesia is frequently seen after dermal exposure to pyrethroids. Affected individuals experience a sensation of burning, tingling, itching, or numbness, most commonly in the face. This occurs 1-2 hours after the beginning of exposure and resolves spontaneously. MECHANISMS Paresthesia occurs as a result of a direct effect on intracutaneous nerve endings at very low pyrethroid doses. It is related to potency of the pyrethroid with pyrethroids without an alpha… CONTINUE READING

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