Pyrazolopyranopyrimidines as a Class of Anti-Inflammatory Agents

@article{Zaki2006PyrazolopyranopyrimidinesAA,
  title={Pyrazolopyranopyrimidines as a Class of Anti-Inflammatory Agents},
  author={M. Zaki and H. Soliman and Ola A Hiekal and A. E. Rashad},
  journal={Zeitschrift f{\"u}r Naturforschung C},
  year={2006},
  volume={61},
  pages={1 - 5}
}
  • M. Zaki, H. Soliman, +1 author A. E. Rashad
  • Published 2006
  • Chemistry, Medicine
  • Zeitschrift für Naturforschung C
  • Abstract Pyrazolopyranopyrimidines 6a-c and 8a-c were prepared from the reaction of compounds 4a-c or 7a-c with methylamine or ammonium hydroxide solutions. Treatment of compounds 6a-c or 8a-c with 2-chloroethyl methyl ether afforded their corresponding acyclonucleosides 9a-c or 10a-c, respectively, as a new class of acyclonucleosides. All prepared compounds were tested as anti-inflammatory agents and some of them revealed moderate to potent antiinflammatory activity 
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