Pyrazolo[3,4-d]pyrimidines as the inhibitors of mycobacterial β-oxidation trifunctional enzyme


Tuberculosis, one of the oldest known human diseases, is still one of the major causes of mortality. Mycobacterium, a genus of Actinobacteria, is responsible for tuberculosis (Mycobacterium tuberculosis) and leprosy (Mycobacterium leprae). Because of producing high toxicity and resistance of existing drugs, the antitubercular drugs with less toxicity… (More)
DOI: 10.1007/s00044-015-1441-6


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