Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia.

@article{Sun2014Pygo2R,
  title={Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia.},
  author={Peng Sun and Kazuhide Watanabe and Magid Fallahi and Briana Lee and Megan E Afetian and Catherine Rh{\'e}aume and Di Wu and Valerie Horsley and Xing Dai},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2014},
  volume={111 28},
  pages={10215-20}
}
Understanding the epigenetic mechanisms that control the activation of adult stem cells holds the promise of tissue and organ regeneration. Hair follicle stem cells have emerged as a prime model to study stem cell activation. Wnt/β-catenin signaling controls multiple aspects of skin epithelial regeneration, with its excessive activity promoting the… CONTINUE READING