• Corpus ID: 27873893

Pycnogenol(®) treatment inhibits bone mineral density loss and trabecular deterioration in ovariectomized rats.

@article{Huang2015PycnogenolTI,
  title={Pycnogenol({\textregistered}) treatment inhibits bone mineral density loss and trabecular deterioration in ovariectomized rats.},
  author={Gang-yong Huang and Jian-guo Wu and Siqun Wang and Yi-bing Wei and Fei-yan Chen and Jie Chen and Jingsheng Shi and Jun Xia},
  journal={International journal of clinical and experimental medicine},
  year={2015},
  volume={8 7},
  pages={
          10893-901
        }
}
CONTEXT Pycnogenol(®) extracted from French maritime pine bark (Pinus pinaster Ait. subsp. atlantica) is functional for its antioxidant activity. OBJECTIVE To investigate the effects of Pycnogenol(®) on bone mineral density (BMD), trabecular microarchitecture and bone metabolism in ovariectomized (OVX) rats. MATERIALS AND METHODS Thirty Sprague-Dawley rats were randomized into 3 groups: SHAM group (sham-operated rats), OVX group (OVX rats), and treatment group (OVX rats supplemented with 40… 

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