Pxl1p, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast.

@article{Ge2008Pxl1pAP,
  title={Pxl1p, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast.},
  author={Wanzhong Ge and Mohan K Balasubramanian},
  journal={Molecular biology of the cell},
  year={2008},
  volume={19 4},
  pages={
          1680-92
        }
}
Paxillins are a family of conserved LIM domain-containing proteins that play important roles in the function and integrity of the actin cytoskeleton. Although paxillins have been extensively characterized by cell biological and biochemical approaches, genetic studies are relatively scarce. Here, we identify and characterize a paxillin-related protein Pxl1p in the fission yeast Schizosaccharomyces pombe. Pxl1p is a component of the fission yeast actomyosin ring, a structure that is essential for… CONTINUE READING

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